Dr Santosh Rao has recently completed a term as President of the Society for Integrative Oncology, a leading force in the drive for integration in cancer care, and now works at the Cleveland Clinic. Unusually, he is qualified in both Oncology and Integrative Oncology and he has a passion for bringing these two worlds together. In this episode, Dr Rao reviews progress in the integrative movement in recent years, and discusses the therapeutic relationship and the enormous potential that is inherent in it to improve patients wellbeing and outcomes through person-centred care, and the conscious utilisation of the placebo effect.