Adriano Dos Santos shares some of the surprising science around chronobiology and lifestyle in cancer care.

Chronobiology, the science of circadian rhythms and the ways in which our own inbuilt biological clocks relate to those around us and to the cycles of nature and the comos, is a rapidly evolving field, uncovering some startling information, much of which is directly of interest to anyone looking to recover from a diagnosis of cancer. A few years ago, who would have imagined that the time of day that a chemotherapy treatment is delivered could have an enormous impact on the success of the treatment? Adriano Do Santos specialises in this field and in this episode he brings us up to date on the latest scientific findings.

• Adriano Dos Santos, AdS Vitality
• Free chronotype test

References from the show:

• SAD Lamp
• Zero Bluelight table lamp

Research papers:

• Fishbein et al. (2021). Circadian disruption and human health. J Clin Invest. 131(19):e148286. DOI: 10.1172/JCI148286
  Berisha et al. (2022). Sleep disruption and cancer: chicken or the egg? Front Neurosci. 16:856235. DOI: 10.3389/fnins.2022.856235
• Malhan, Relógio et al. (2025). Circadian rhythm disruption by PARP inhibitors correlates with treatment toxicity in ovarian cancer patients. EBioMedicine. 117:105764. DOI: 10.1016/j.ebiom.2025.105764
• Nelson, Relógio et al. (2025). Personalized chronotherapy in glioblastoma. NPJ Precis Oncol. 10(1):17. DOI: 10.1038/s41698-025-01205-z
• Almonte, Derosa, Zitvogel et al. (2026). Gut dysbiosis in oncology: a risk factor for immunoresistance. Cell Research. 36(2):103–120. DOI: 10.1038/s41422-025-01212-6